Researchers identify proteins that could help diagnose Kawasaki disease early

March 21, 2017 (Mainichi, Japan)

March 21, 2017

A research team from Yokohama City University has identified four types of protein that could be used to diagnose “Kawasaki disease” at an early stage. The discovery is important because it will hopefully lead to a reduction in heart complications that occasionally develop as a result of the illness.

Yokohama City University associate professor Yayoi Kimura and her team of fellow researchers observed that the concentration levels of four different proteins — LBP, LRG1, AGT and RBP4 — changed during the acute or early phase of Kawasaki disease.

These findings are significant because the disease is known for being difficult to diagnose during the acute stage. There are at least five prominent symptoms, such as fever, red eyes and rash. But because it takes between three to seven days for these symptoms to appear altogether, even experts hesitate to commence treatment before all the symptoms are there.

Therefore, in the future, if doctors are able to identify protein-level related changes during the acute phase of Kawasaki disease, it should facilitate an earlier diagnosis, and hence enable treatment to commence more quickly. In cases where symptoms persist for 10 days or so after onset, and are not treated, heart complications such as coronary artery disease can develop in 25 to 30 percent of patients.

Having made this discovery, Yokohama City University now intends to test a diagnostic agent in clinical trials from fiscal 2017 onward, in collaboration with a Japanese company, having already applied for an international patent. Looking ahead, Kimura is positive. “We are hoping that our findings can be used in four to five years time to make actual diagnoses.”

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Please join us on Saturday, April 22, 2017

SickKids Labatt Family Heart Centre - 2017 Family Conference - Toronto, Ontario

March 21, 2017

We are proud to be participating in this year’s SickKids Labatt Family Heart Centre Family Conference.

The conference is taking place on Saturday, April 22, 2017 at the Peter Gilgan Centre for Research and Learning at SickKids in Toronto, ON. This is a great opportunity to meet other families that have been affected by Kawasaki disease.

If you would like more information or to register, please email us at:

We hope to see you there!

Fairchild TV Timeline Magazine

Episode about Kawasaki Disease

February 28, 2017

Thanks to Fairchild TV for featuring Kawasaki disease on their Cantonese language Timeline Magazine program that aired on February 22.  Kawasaki Disease Canada was glad to play a role in facilitating the production of this piece that highlights the symptoms and treatment of Kawasaki disease, the possible long term effects, as well as some of the latest Canadian research.

We are pleased to be part of raising awareness of Kawasaki disease among Fairchild TV’s 500,000 Cantonese speaking viewers.

Click here to watch the piece: Fairchild TV Timeline Magazine Episode